WebJan 1, 2024 · Download Citation Synthetic circular RNA for protein expression Messenger RNA (mRNA) has broad potential for therapeutic and engineering applications. One … WebJan 2, 2024 · RNA switches are one class of gene-regulatory elements that control protein expression in a manner that is dependent on the concentration of specific ligand molecules. ... RNA Switches for Synthetic Biology Cold Spring Harb Perspect Biol. 2024 Jan 2;11(1):a032532. doi: 10.1101/cshperspect.a032532.
Synthetic circular RNA switches and circuits that control protein ...
WebThe circular RNA renaissance is upon us. Recent reports demonstrate applications of synthetic circular RNA molecules as gene therapies and in the production of biologics … WebFeb 4, 2024 · A synthetic protein quality control system ... Engineering circular RNA for enhanced protein production. 18 July 2024. ... a Design of gene expression cassette of the Circ-RNA system and the Lin ... prince andy \u0026 the paedo
RNA Switches for Synthetic Biology - PubMed
WebJan 4, 2024 · a Following transcription, mRNAs are spliced by the spliceosome, a complex of small nuclear RNAs (snRNA) and proteins, and matured by the addition of markers … WebNov 24, 2024 · To experimentally test whether circRNAs can efficiently function as protein sponges, we designed, expressed and characterized artificial circRNAs as sponges for hnRNP L. HnRNP L, a classical RNA-binding protein with four RNA-recognition motifs (RRMs), can function either as splice activator or repressor, requiring binding to short CA … WebCircular RNAs (circRNAs) are stable and prevalent RNAs in eukaryotic cells that arise from back-splicing. Synthetic circRNAs and some endogenous circRNAs can encode proteins, … prince a new york film complet